Calcium Subspace Beta-Cell Model

In this model, the Ca2+-activated K+ channel is governed by Ca2+ released from the ER into a small subspace between the ER and the plasma membrane.

Paper 1: Goforth et al, J. Gen. Physiol., 120(3):307-322, September, 2002. [PubMed]

Summary of equations for Paper 1: Appendix 1

Paper 2: Zhang et al, Biophys. J. 84:2852-2870. 2003. [PubMed]

Summary of equations for Paper 2: Appendix 2

Paper 3: Zhang et al., Disruption of native gap junctions prevents physiological bursing and calcium synchronization in mouse pancreatic islets, in preparation.

Summary of equations for Paper 3: Appendix 3